Shailesh.Appukuttanappukuttan.shailesh@gmail.com

Archives: Publications

We have attempted to reproduce a biologically-constrained point-neuron model of CA1 pyramidal cells. The original models, developed for the Brian simulator, captured the frequency-current profiles of both strongly and weakly adapting cells. As part of the present study, we reproduced the model for different simulators, namely Brian2 and NEURON. The reproductions were attempted independent of […]

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Archives: Publications

Archives: Publications

Synchronization of network oscillation in spatially distant cortical areas is essential for normal brain activity. Precision in synchronization between hemispheres depends on the axonal conduction velocity, which is determined by physical parameters of the axons involved, including diameter, and extent of myelination. To compare these parameters in long-projecting excitatory and inhibitory axons in the corpus […]

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Archives: Publications

In the last decades, brain modeling has been established as a fundamental tool for understanding neural mechanisms and information processing in individual cells and circuits at different scales of observation. Building data-driven brain models requires the availability of experimental data and analysis tools as well as neural simulation environments and, often, large scale computing facilities. […]

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